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ABCG2 antibody [BXP-21]

Cat. No. GTX23380

Host

Mouse

Clonality

Monoclonal

Clone Name

BXP-21

Isotype

IgG2a

Application

WB, ICC/IF, IHC-P, IHC-Fr, FACS

Reactivity

Human
Package
250 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF 1:20-1:50
IHC-P Assay dependent
IHC-Fr 1:20
FACS Assay dependent
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Product Note

Reacts with an internal epitope of BCRP. Does not cross-react with the human MDR1, MRP1, MRP2 gene products.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant (Serum free medium), 0.7% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

fusion protein containing human BCRP (amino acids 271-396) and maltose-binding protein.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_379784

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ATP binding cassette subfamily G member 2 (Junior blood group) , ABC15 , ABCP , BCRP , BCRP1 , BMDP , CD338 , CDw338 , EST157481 , GOUT1 , MRX , MXR , MXR-1 , MXR1 , UAQTL1

Cellular Localization

Cell membrane

Background

Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.

Database

Research Area

REFERENCE

REVIEW

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Application Reference
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399