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FGFR2 antibody

Anti-FGFR2 antibody used in Western Blot (WB). GTX81341
Anti-FGFR2 antibody used in Western Blot (WB). GTX81341
Anti-FGFR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX81341
Anti-FGFR2 antibody used in IHC (Paraffin sections) (IHC-P). GTX81341
Anti-FGFR2 antibody used in Flow cytometry (FACS). GTX81341

Cat. No. GTX81341

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, FACS

Reactivity

 Human
Package
400 μl ($399)
See all FGFR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:10-1:50
IHC-P 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

92 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This FGFR2 antibody is generated from rabbits immunized with a his tag recombinant protein of human FGFR2.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fibroblast growth factor receptor 2 , BBDS , BEK , BFR-1 , CD332 , CEK3 , CFD1 , ECT1 , JWS , K-SAM , KGFR , TK14 , TK25

Cellular Localization

Cell membrane; Single-pass type I membrane protein,Golgi apparatus,Cytoplasmic vesicle

Background

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

Database

Research Area

DATA IMAGES

Anti-FGFR2 antibody used in Western Blot (WB). GTX81341

GTX81341 WB Image

WB analysis of 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FGFR2 (Lane 2) using GTX81341 FGFR2 antibody.

Anti-FGFR2 antibody used in Western Blot (WB). GTX81341

GTX81341 WB Image

WB analysis of NCI-H460 cell lysate (35ug/lane) using GTX81341 FGFR2 antibody.

Anti-FGFR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX81341

GTX81341 ICC/IF Image

ICC/IF analysis of U251 cells using GTX81341 FGFR2 antibody.
Green : FGFR2
Blue : DAPI

Anti-FGFR2 antibody used in IHC (Paraffin sections) (IHC-P). GTX81341

GTX81341 IHC-P Image

IHC-P analysis of human lung carcinoma using GTX81341 FGFR2 antibody.

Anti-FGFR2 antibody used in Flow cytometry (FACS). GTX81341

GTX81341 FACS Image

FACS analysis of U251 cells using GTX81341 FGFR2 antibody.
Right histogram : U251 cells
Left histogram : negative control

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399