Primary Antibodies

Articles

IVD-related Products and Services

Articles

A Review of the SARS-CoV-2 (COVID-19) Genome and Proteome

GeneTex is proud to offer an extensive line of reagents to support the study of SARS-CoV-2 / COVID-19.

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GeneTex’s “5 + 1” Pillar Antibody Validation Process

GeneTex employs various analytic validation strategies to ensure both consistent quality and specificity.

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The concept of a SARS-CoV-2 / COVID-19 rapid test

A rapid virus antigen test detects SARS-CoV-2 particles in samples by capturing viral antigen between a free labeled antibody and a fixed second antibody that each recognize different regions of the antigen.

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Antibodies for Flow Cytometry

Conjugated Monoclonal Antibodies Most Popular Clones

Articles

beta Amyloid

GeneTex’s “beta-Amyloid (1-42) antibody – Conformation-Specific” can specifically detect amyloid plaques in the Alzheimer's Disease brain by IHC-P analysis. The superior specificity and sensitivity of this antibody were confirmed by dot blot, ELISA and side-by-side IHC-P comparison with competitor's.

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Approach to Antibody Lot-to-Lot Variability

Lot-to-lot variability is a persistent quality control (QC) issue that contributes to inconsistent results in assays using antibodies.

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Overexpression Antibodies

The validity of a target protein’s endogenous signal can be further substantiated through overexpression of that protein using a recombinant construct.

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Orthogonal_Antibodies

Detecting predicted changes in the antibody-generated signal due to alteration of experimental biological conditions is a reliable approach to gauge antibody performance.

Articles

IP/MS-antibodies

Using mass spectrometry (MS) to identify the protein(s) bound by an antibody is a powerful method for the validation of antibody specificity and performance.

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Knockdown Technology

RNA interference (RNAi) refers to a cellular mechanism of post-transcriptional gene regulation through the actions of non-coding microRNAs (miRNAs).

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Background of CRISPR/Cas9 technology

The RNA-guided CRISPR/Cas9 system is a revolutionary genome editing tool derived from the bacterial Type II CRISPR adaptive immune system.

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Comparable antibodies

Comparing the signals generated by two independent antibodies for the same protein target in different samples is a practical way to test antibody specificity.

Articles

Knockout/Knockdown Validation

GeneTex is conducting knockout/knockdown-based validation as a fundamental component of its antibody quality assurance process.

Articles

ResponsibleScientists.org

An Open Letter Regarding Climate Change From Concerned Members of the U.S. National Academy of Sciences

Pathways

Epithelial–mesenchymal transition (EMT) Pathway

EMT is a process whereby tightly-interacting and immotile epithelial cells acquire the phenotype of loosely-adherent and motile mesenchymal cells.

Pathways

Autophagy Pathway

Autophagy is the process of self-cannibalization of cellular proteins or organelles through lysosomal degradation.

Pathways

Bcl-2 Pathway

B-cell lymphoma-2 (Bcl-2)-family proteins play an important role in regulating the induction of apoptosis.

Pathways

Notch Pathway

The Notch signaling pathway is an important evolutionarily conserved pathway that plays a vital role in the regulation of asymmetric cell division, cell fate specification, proliferation and apoptosis during development.

Pathways

Apoptosis Pathway

Pathways

Cell Cycle Pathway

Pathways

Histone Code

Pathways

JAK-STAT Pathway

Pathways

Hypoxia Pathway

Hypoxia in tumors is closely associated with tumor aggressiveness and resistance to radio- and chemotherapeutic treatment.

Pathways

ER Stress Pathway

Newsletter

Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In NSCLC

Article Alert: Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In Non-Small Cell Lung Cancer

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Acquired Resistance to Immunotherapy is Mediated by EMT and Irf6 Repression in Pancreatic Cancer

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Article Alert: Stromal Monoamine Oxidase B Drives Prostate Cancer

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Article Alert: Exosomal lnc-MLETA1 Promotes Lung Cancer Metastasis

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Article Alert: An anti-VEGFR2 F(ab')2 Drug Conjugate as a Therapeutic Agent for Diabetic Nephropathy

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Article Alert: Capsid-dependent Choreography of HIV-1 Nuclear Entry

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GeneTex's KO-Validated RGS4 Recombinant Monoclonal Antibody

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GeneTex's GAD67 and GAD65 Recombinant Monoclonal Antibodies

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GeneTex’s New Recombinant Monoclonal CD97/ADGRE5 Antibody

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Detection of VEEV Nonstructural Proteins with GeneTex’s Recombinant Monoclonal Antibodies

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GeneTex’s Monoclonal Antibodies for EGFR Research

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Influenza A and B Virus Recombinant Monoclonal Antibodies

Influenza A and B Virus Recombinant Monoclonal Antibodies

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The SARS-CoV-2 Omicron Variant

The SARS-CoV-2 Omicron Variant

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GeneTex’s “5 + 1” Pillar Antibody Validation Plan

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Omicron BQ.1 and BF.7 Spike and Nucleocapsid Recombinant Proteins

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A Rising StAR in Cancer Research

Steroidogenic acute regulatory protein 1 (StAR/StARD1) mediates the rate-limiting step in steroidogenesis...

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SARS-CoV-2-directed T cell Response in Convalescent and Vaccinated Individuals

SARS-CoV-2-directed T cell Response in Convalescent and Vaccinated Individuals

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SARS-CoV-2 can infect the human brain

SARS-CoV-2 can infect the human brain

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Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

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IHC- and FCM-validated Antibodies for SARS-CoV-2 Research

IHC- and FCM-validated Antibodies for SARS-CoV-2 Research

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Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)

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New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2

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Article alert: Proteomic Analysis Reveals How RNA Viruses Remodel Host Polysomes

Article alert: Proteomic Analysis Reveals How RNA Viruses Remodel Host Polysomes

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Skin Regeneration without Scar Formation

Skin Regeneration without Scar Formation

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mRNA Vaccine-induced Antibody Profiles against SARS-CoV-2 Variants

mRNA Vaccine-induced Antibody Profiles against SARS-CoV-2 Variants

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GeneTex’s SARS-CoV-2 Spike RBD Antibodies Effectively Inhibit Viral Entry

GeneTex’s SARS-CoV-2 Spike RBD Antibodies Effectively Inhibit Viral Entry

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Neuropilins Facilitate SARS-CoV-2 Entry into Host Cells

Neuropilins Facilitate SARS-CoV-2 Entry into Host Cells

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Zika Virus Infection Increases Risk of Subsequent Severe Dengue Disease

Zika Virus Infection Increases Risk of Subsequent Severe Dengue Disease

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GeneTex SARS-CoV-2 (COVID-19) Nucleocapsid Protein Sandwich ELISA Kit

This kit allows highly specific, ultrasensitive detection of SARS-CoV-2 N protein with an average lowest detection limit of 18 pg/ml.

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GeneTex Introduces Recombinant Monoclonal Iba1 Antibody

GeneTex's Iba1 recombinant antibody is suitable for IHC staining and WB.

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GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex's RAS (G12D mutant) recombinant antibody is suitable for IHC staining and WB.

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Leaky blood-brain barrier triggers neural dysfunction that is reversible

Leaky blood-brain barrier triggers neural dysfunction that is reversible

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GeneTex Partners With BenchSci to Augment Antibody Catalog Publication Data

Partnership will use BenchSci's artificial intelligence to help researchers run successful experiments with the right antibody

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GeneTex Webinar Series

GeneTex Webinar Series

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SARS-CoV-2 Proteins and Antibodies for Lateral Flow-based Neutralization Assay

for Lateral flow-based Neutralization Assay

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A Cancer Immunotherapy Holy Grail?

A Cancer Immunotherapy Holy Grail?

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MLLT3/AF9 is Pivotal for Human HSC Self-renewal and Engraftment

MLLT3/AF9 is Pivotal for Human HSC Self-renewal and Engraftment

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Independent Knockout Validation of C9ORF72 Antibodies

Independent Knockout Validation of C9ORF72 Antibodies for the research of Amyotrophic lateral sclerosis.

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Is ApoE the piece to complete the puzzle of Alzheimer’s disease?

ApoE was identified as a major checkpoint inhibitor of the classical complement cascade, and involved in a possible unifying mechanism underlying Alzheimer’s disease, atherosclerosis, and potentially other inflammatory diseases.

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A Well-Cited Nrf2 Antibody for Cellular Redox Research

A quality Nrf2 antibody with multiple species reactivity for cellular redox research

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Neurodegeneration: A "Vicious Cycle" Involving Mitochondria, Glia, and Neuronal Death

A "Vicious Cycle" Involving Mitochondria, Glia, and Neuronal Death

Newsletter

SETD3 Is Pivotal for Infection by Multiple Human Enteroviruses

In an exciting example of this concept, Diep et al. described the use of a genome-scale CRISPR screen to show that the protein histidine methyltransferase SETD3 is crucial for the replication of multiple human enteroviruses.

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Soluble TREM2 is associated with clinical progression of Alzheimer’s disease.

A recent study by Ewers et al. reported that increased soluble TREM2 measured in cerebrospinal fluid was associated with lower rates of cognitive and clinical decline and progression in people with AD.

Newsletter

Adoptive T cell therapy shows potential to eliminate hepatitis B virus (HBV) infection.

Is a cure for chronic hepatitis B on the horizon? Adoptive T cell therapy shows potential to eliminate hepatitis B virus (HBV) infection.

Newsletter

Improving cancer immunotherapy efficacy may depend on targeting exosomes

Improving cancer immunotherapy efficacy may depend on targeting exosomes bearing the immune checkpoint protein PD-L1

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Antibodies in trial size. 25μl package available now!

Our most popular antibodies now come in 25μl packaging.